Choline, also known as vitamin B4, is a water-soluble vitamin essential for human health.
Human body can produce choline in the liver, but not in sufficient amount. As a result, we must obtain choline from our diet.
The vast majority of population don’t get enough choline (1).
Choline regulates fat and cholesterol absorption in the liver and help in its detoxification (2).
Choline can help reduce levels of homocysteine in the blood, and reduce the risk of cardiovascular disease (1).
Choline is required to make acetylcholine which is an important neurotransmitter involved in memory, muscle movement and heartbeat regulation (3).
Recommended Daily Allowance for a 44-year-old male moderately active, weighting 70 kg and 175 cm tall is 550 mg and the Tolerable Upper Intake is 3 500 mg (4).
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The signs and symptoms of choline deficiency may include:
Too much choline is associated with: